Ertugliflozin

Ertugliflozin
  • Orukọ:Ertugliflozin
  • Katalogi No.CPD0004
  • CAS No.:1210344-57-2
  • Ìwọ̀n Molikula:436.88
  • Fọọmu Kemikali:C22H25ClO7
  • Fun iwadi ijinle sayensi nikan, kii ṣe fun awọn alaisan.

    Alaye ọja

    ọja Tags

    Iwọn Pack Wiwa Iye owo (USD)

    Orukọ Kemikali:

    (1S,2S,3S,4R,5S) -5- (4-chloro-3- (4-ethoxybenzyl) phenyl) -1- (hydroxymethyl) -6,8-dioxabicyclo [3.2.1] octane-2,3 ,4-triol

    KỌỌDỌ SMILES:

    "CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl"

    Koodu InChi:

    "InChi=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) 18(25)19(2 6)21 (11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+ ,21-,22-/m0/s1 "

    Bọtini InChi:

    "MCIACXAZCBVDEE-CUUWFGFTSA-N"

    Koko-ọrọ:

    Ertugliflozin, PF 04971729,MK-8835,1210344-57-2

    Solubility:Tiotuka ni DMSO

    Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu).

    Apejuwe:

    Ertugliflozin, ti a tun mọ bi a tun mọ bi PF-04971729, jẹ oludena ti o lagbara ati yiyan ti iṣuu soda-ti o gbẹkẹle glukosi cotransporter 2 ati oludije ile-iwosan fun itọju iru àtọgbẹ 2. Iwadi ile-iwosan fihan pe Ertugliflozin (1-25 mg / ọjọ) ni ilọsiwaju iṣakoso glycemic, iwuwo ara ati titẹ ẹjẹ ni awọn alaisan ti o ni iṣakoso suboptimally T2DM lori metformin, ati pe o farada daradara.

    Àkọlé: SGLT-2


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