DEL-22379
Alaye ọja
ọja Tags
| Iwọn Pack | Wiwa | Iye owo (USD) |
| 100mg | O wa | 350 |
| 250mg | O wa | 600 |
| 1g | O wa | 1200 |
| Awọn iwọn diẹ sii | Gba Awọn asọye | Gba Awọn asọye |
Orukọ Kemikali:
(Z) - N- (3- ((5-methoxy-1H-indol-3-yl) methylene) -2-oxoindolin-5-yl) -3- (piperidin-1-yl) propanamide.
KỌỌDỌ SMILES:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Koodu InChi:
InChi=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22)32)28-25 (31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2, 1H3,(H,28,31)(H,29,32)/b22-13+
Bọtini InChi:
INQUULPXCZAKMS-LPYMAVHISA-N
Koko-ọrọ:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solubility:Tiotuka ni DMSO
Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu)
Apejuwe:
DEL-22379 jẹ oludaniloju ERK Dimerization ti o lagbara ati yiyan. DEL-22379 ṣe idiwọ ERK Dimerization laisi ni ipa ERK phosphorylation, ṣe idiwọ tumorigenesis ti o wa nipasẹ ọna RAS-ERK oncogenes. O fẹrẹ to 50% ti awọn aiṣedeede eniyan ṣe afihan ifihan RAS-ERK ti ko ni ilana; idinamọ o jẹ ilana ti o wulo fun ilowosi antineoplastic.
afojusun: ERK
