Ciforadenant

Orukọ Kemikali:

(S) -7- (5-methylfuran-2-yl) -3- ((6-(((tetrahydrofuran-3-yl) oxy) methyl) pyridin-2-yl) methyl) -3H-[1,2 ,3]triazolo [4,5-d] pyrimidin-5-amine

KỌỌDỌ SMILES:

NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1

Koodu InChi:

InChi=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3- 2-4-14 (22-13) 10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/t15- /m0/s1

Bọtini InChi:

KURQKNMKCGYWRJ-HNNXBMFYSA-N

Koko-ọrọ:

Ciforadenant, CPI-444, V81444, CPI444, CPI 444

Solubility:Tiotuka ni DMSO

Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu)

Apejuwe:

CPI-444 jẹ alagbara, ẹnu ti o wa, antagonist yiyan ti adenosine A2A receptor ti o ti farada daradara ni awọn ẹkọ Ph 1 / 1b ni awọn itọkasi ti kii-oncology.

Ifojusi: Adenosine A2A