BAZ2-ICR
Alaye ọja
ọja Tags
| Iwọn Pack | Wiwa | Iye owo (USD) |
| 100mg | O wa | 500 |
| 500mg | O wa | 800 |
| 1g | O wa | 1200 |
| Awọn iwọn diẹ sii | Gba Awọn asọye | Gba Awọn asọye |
Orukọ Kemikali:
4- (4- (1-methyl-1H-pyrazol-4-yl) -1- (2- (1-methyl-1H-pyrazol-4-yl) ethyl) -1H-imidazol-5-yl) benzonitrile
KỌỌDỌ SMILES:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
Koodu InChi:
InChi=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27) 17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
Bọtini InChi:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
Koko-ọrọ:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Solubility:Tiotuka ni DMSO
Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu).
Apejuwe:
BAZ2-ICR jẹ iwadii kemikali ti o dara julọ fun awọn iṣẹ ṣiṣe ti BAZ2 bromodomains in vitro ati in vivo. Bromodomain ti o ni awọn ọlọjẹ BAZ2A/B ṣe awọn ipa pataki ninu atunṣe chromatin ati ilana ti awọn RNA ti kii ṣe koodu. BAZ2-ICR ni IC50 (BAZ2A) = 130 nM; IC50 (BAZ2B) = 180 nM; logD = 1.05; solubility 25 mM (D2O) ati F = 70%.
Ifojusi: BAZ2