CB-839
Iinkcukacha zeMveliso
Iithegi zeMveliso
| Ubungakanani bePakethi | Ubukho | Ixabiso (USD) |
| 100mg | Ikhona evenkileni | 500 |
| 500mg | Ikhona evenkileni | 800 |
| 1g | Ikhona evenkileni | 1200 |
| Iisayizi ezininzi | Fumana iiQuotes | Fumana iiQuotes |
Igama leMchiza:
2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl)i-acetamide
Ikhowudi yoncumo:
O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4
Ikhowudi ye-InChi:
InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24- 35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7, 10,15-16H2,(H,31,34,37)(H,32,36,38)
Isitshixo se-InChi:
PRAAPINBUWJLGA-UHFFFAOYSA-N
Igama elingundoqo:
CB-839, CB839, CB 839, 1439399-58-2
Ukunyibilika:Inyibilika kwi-DMSO
Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga).
Inkcazo:
"I-CB-839 i-inhibitor ye-bioavailable yomlomo ye-glutaminase, kunye nomsebenzi onokuthi ube ne-antineoplastic. Ekulawuleni komlomo, i-CB-839 ngokukhethayo kwaye ingenakuguqulwa inqanda i-glutaminase, i-enzyme ye-mitochondrial ebalulekileyo ekuguqulweni kwe-amino acid glutamine nge-blocking glutamine. ukusetyenziswa, ukwanda kwiiseli ezikhula ngokukhawuleza amathumba axhomekeke kwi-Glutamine axhomekeke ekuguquleni i-glutamine yangaphandle ibe yi-glutamate kunye ne-glutamate metabolites ukuze zombini zinike amandla kunye nokuvelisa iibhloko zokwakha ukuveliswa kwee-macromolecules, ezifunekayo ekukhuleni kweselula kunye nokuphila ".
Ithagethi: Glutaminase
