diABZI STING agonist-1

Himiki ady:

(E) -1- (4- (5-karbamoýl-2- -1-ýyl) ýöne-2-en-1-ýyl) -2- (1-etil-3-metil-1H-pirazol-5-karboksamido) -7-metoksi-1H-benzo [d] imidazol-5- karboksid

SMILES kody:

O = C (N) C1 = CC (N = C (NC (C2 = CC (C) = NN2CC) = O) N3C / C = C / CN4C (NC (C5 = CC (C) = NN5CC) = O) = NC6 = C4C (OCCCN7CCOCC7) = CC (C (N) = O) = C6) = C3C (OC) = C1

InChi kody:

InChI = 1S / C42H51N13O7 / c1-6-54-31 (19-25 (3) 49-54) 39 (58) 47-41-45-29-21-27 (37 (43) 56) 23-33 ( 60-5) 35 (29) 52 (41) 12-8-9-13-53-36-30 (46-42 (53) 48-40 (59) 32-20-26 (4) 50-55 (32) 7-2) 22-28 (38 (44) 57) 24-34 (36) 62-16-10-11-51-14-17-61-18-15-51 / h8- 9,19-24H, 6-7,10-18H2,1-5H3, (H2,43,56) (H2,44,57) (H, 45,47,58) (H, 46,48,59) / b9-8 +

InChi açary:

JGLMVXWAHNTPRF-CMDGGOBGSA-N

Açar söz:

Çözüw: 

Saklama: 

Düşündiriş:

diABZI STING agonist-1, degişlilikde adam we syçan üçin EC50s 130, 186 nM bolan interferon genleriniň (STING) reseptor agonistiniň saýlaýjy stimulýatorydyr.

Maksat: STING