diABZI STING agonist-1 (Tautomerizm)

Himiki ady:

(E) -1 - ((E) -4 - ((E) -5-karbamoyl-2 - ((1-etil-3-metil-1H-pirazol-5-karbonil) imino) -7- (3- morfolinopropoksi) -2,3-dihidro-1H-benzo [d] imidazol-1 ýyl) ýöne-2-en-1 ýyl) -2 - ((1-etil-3-metil-1H-pirazol-5-) karbonil) imino) -7-metoksi-2,3-dihidro-1H-benzo [d] imidazol-5-karboksamid

SMILES kody:

O = C (N) C1 = CC (N / C (N2C / C = C / CN3 / C) (NC4 = C3C (OCCCN5CCOCC5) = CC (C (N) = O) = C4) = N / C (C6 = CC (C) = NN6CC) = O) = NC (C7 = CC (C) = NN7CC) = O) = C2C (OC) = C1

InChi kody:

InChI = 1S / C42H51N13O7 / c1-6-54-31 (19-25 (3) 49-54) 39 (58) 47-41-45-29-21-27 (37 (43) 56) 23-33 ( 60-5) 35 (29) 52 (41) 12-8-9-13-53-36-30 (46-42 (53) 48-40 (59) 32-20-26 (4) 50-55 ( 32) 7-2) 22-28 (38 (44) 57) 24-34 (36) 62-16-10-11-51-14-17-61-18-15-51 / h8-9,19- 24H, 6-7,10-18H2,1-5H3, (H2,43,56) (H2,44,57) (H, 45,47,58) (H, 46,48,59) / b9-8 +

InChi açary:

JGLMVXWAHNTPRF-CMDGGOBGSA-N

Açar söz:

Çözüw: 

Saklama: 

Düşündiriş:

diABZI STING agonist-1 Tautomerizm (3-nji goşundy), adam we syçan üçin EC50s 130, 186 nM bolan interferon genleriniň (STING) reseptor agonistiniň saýlaýjy stimulýatorydyr.

Maksat: STING