LX-2761
Faahfaahinta Alaabta
Tags Product
| Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
N- (1- (2- (2- (Dimethylamino) ethyl)amino) -2-methyl-1-oxopropan-2-yl) -4- (2-methyl-5-(2S,3R,4R, 5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl) benzyl) phenyl) -butanamide
Koodhka dhoola cadeynta:
O=C(NC(C)(C)C(NCCN(C)C)=O)CCCC1=CC=C(CC2=CC([C@H]3[C@H](O)[C@@ H](O)[C@H](O)[C@@H](SC)O3=CC=C2C)C=C1
Koodhka InChi:
InChi=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20)18-22- 13-11-21 (12-14-22)8-7-9-25(36)3 4-32 (2,3)31 (40)33-16-17-35(4)5/h10-15,19,26-30,37-39H,7-9, 16-18H2,1-6H3,(H,33,40)(H,34,36)/t26-,27-,28+,29+,30-/m1/s1
Furaha InChi:
BNPZTRDIESRGTC-IXYVTWBDSA-N
Ereyga muhiimka ah:
LX-2761, LX2761, LX 2761, 1610954-97-6
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).
Sharaxaad:
LX2761 waa ka hortag maxalli ah oo SGLT1 ah kaas oo aad u awood badan in vitro oo dib u dhigaya nuugista gulukooska mindhicirka ee vivo si loo hagaajiyo xakamaynta glycemic. LX2761 ayaa leh hSGLt1 2.2 nM; hSGLT2 2.7 nM iyo F% =<2. LX2761 waa unug aad u awood badan, kiimiko ahaan deggan, iyo unugyo iftiin leh oo xaddidan oo helay caddaynta fikradda OGTT qiyaaso aad u hooseeya. LX2761 waxaa loogu talagalay inuu ku sii jiro mindhicirka ka dib dhalmada afka si loo joojiyo SGLT1 gudaha iyada oo aan saameyn ku yeelan habka SGLT1/2 ee kelyaha.
Ujeedka: SGLT1
