GSK2982772

GSK2982772
  • Magaca:GSK2982772
  • Lambarka buugga:CPDD1123
  • Lambarka CAS:1622848-92-3
  • Miisaanka Molecular:377.404
  • Foomka Kiimikada:C20H19N5O3
  • Cilmi baaris cilmiyeed oo keliya, ma ahan bukaanka.

    Faahfaahinta Alaabta

    Tags Product

    Cabbirka Xidhmada Helitaanka Qiimaha (USD)
    100mg In Stock 500
    500mg In Stock 800
    1g In Stock 1200
    Cabiro badan Hel Xigasho Hel Xigasho

    Magaca Kiimikada:

    (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4] oxazepin-3-yl)-4H-1,2, 4-triazole-3-carboxamide

    Koodhka dhoola cadeynta:

    O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O

    Koodhka InChi:

    InChi=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(2) 3-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24) /t14-/m0/s1

    Furaha InChi:

    LYPAFUINURXJSG-AWEZNQCLSA-N

    Ereyga muhiimka ah:

    GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3

    Xalka:Ku milmay DMSO

    Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

    Sharaxaad:

    GSK2982772 waa soo-dhoweeye awood leh oo la xushay Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate for the Treatment of Inflammatory Diseases. GSK2982772 waa, hadda ku jira marxaladda 2a daraasadaha kiliinikada ee cudurka psoriasis, rheumatoid arthritis-ka, iyo colitis boogaha. GSK2982772 waxay si xoog leh ugu xidhan tahay RIP1 oo leh gaar gaar ah kinase waxayna leedahay hawl aad u wanaagsan oo lagu joojinayo jawaabaha gacanta ee TNF-ku-tiirsanaanta badan. RIP1 waxay u soo baxday kinase muhiim ah oo kor u kaca oo lagu muujiyay in lagu xakameeyo bararka iyada oo loo marayo labadaba labadaba iyo hawlaha gaarka ah ee kinase.

    Ujeedka: RIP1


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