| CAT # | Product Name | Tsanangudzo |
| CPD3611 | SB-204990 | SB-204990 ndiyo prodrug yeakasimba ATP citrate-lyase inhibitor SB-201076. SB-204990, painopihwa nemuromo kumakonzo, yakanyudzwa mukati me systemic kutenderera, pharmacologically yakakosha kutariswa kweSB-201076 yakadzoserwa muchiropa. SB-204990 (25 mg/kg pazuva) zvakare yakaderedza plasma cholesterol mazinga (kusvika kusvika 23%) uye triglyceride mazinga (kusvika kusvika 38%) mumbwa, zvichinyanya kuderera pasi-density lipoprotein kana ichienzaniswa nepamusoro-density lipoprotein cholesterol. mazinga. SB-204990 inzyme yakakosha mukudzora substrate kupihwa kwelipid synthesis de novo uye inogona kuita enzyme tarisiro yekupindira kwe hypolipidemic. |
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