STING

CAT # Product Name Tsanangudzo
CPD101235 DiABZI STING agonist-1 trihydrochloride diABZI STING agonist-1 (trihydrochloride) is a selective stimulator ye interferon genes (STING) receptor agonist, ine EC50s ye130, 186 nM yevanhu nembeva, zvichiteerana.
CPD101234 diABZI STING agonist-1 (Tautomerism) diABZI STING agonist-1 Tautomerism (compound 3) is a selective stimulator ye interferon genes (STING) receptor agonist, ine EC50s ye130, 186 nM yemunhu nembeva, zvichiteerana.
CPD101233 diABZI STING agonist-1 diABZI STING agonist-1 inosarudza inokurudzira ye interferon genes (STING) receptor agonist, ine EC50s ye130, 186 nM yevanhu nembeva, zvichiteerana.
CPD101232 STING agonist-4 STING agonist-4 inosimudzira yeInterferon Genes (STING) receptor agonist ine inooneka inhibitory nguva dzose (IC50) ye20 nM. STING agonist-4 ndeye maviri amidobenzimidazole ane hukama-ane symmetry amidobenzimidazole (ABZI)-yakavakirwa musanganiswa kugadzira akabatana ABZIs (diABZIs) ane inosungirirwa kuSTING uye cellular basa.
CPD101231 STING agonist-3 STING agonist-3, yakatorwa kubva patent WO2017175147A1 (muenzaniso 10), inosarudza uye isiri-nucleotide diki-molecule STING agonist ine pEC50 uye pIC50 ye7.5 uye 9.5, zvichiteerana. STING agonist-3 ine yakasimba anti-tumor mhedzisiro uye yakakura mukana wekuvandudza kurapwa kwegomarara
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