STING agonist-3
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
(E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)asi-2- en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide
SMILES Kodhi:
O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCCO)C3=C1
InChi Code:
InChI=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(32(38)51)10-11- 27(25)46(36)12-7-8-13-47-31-26(19-24(33(39)52)20-30(31)55-15-9-14-50)41- 37(47)43-35(54)29-17-22(4)45-49(29)6-2/h7-8,10-11,16-20,50H,5-6,9,12- 15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8-7+
InChi Key:
VHCDRDBENBVEK-BQYQJAHWSA-N
Keyword:
Solubility:
Kuchengeta:
Tsanangudzo:
STING agonist-3, yakatorwa kubva patent WO2017175147A1 (muenzaniso 10), inosarudza uye isiri-nucleotide diki-molecule STING agonist ine pEC50 uye pIC50 ye7.5 uye 9.5, zvichiteerana. STING agonist-3 ine yakasimba anti-tumor mhedzisiro uye yakakura mukana wekuvandudza kurapwa kwegomarara
Chinangwa: STING