DEL-22379
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 100mg | E tele | 350 |
| 250mg | E tele | 600 |
| 1g | E tele | 1200 |
| Tele Tele | Maua Upusii | Maua Upusii |
Igoa vaila'au:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl) propanamide
SMILES Code:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
InChi Code:
InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26(22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28) ,31)(H,29,32)/b22-13+
InChi Key:
INQUULPXCZAKMS-LPYMAVHISA-N
upu autu:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)
Fa'amatalaga:
DEL-22379 o se malosi ma filifilia ERK Dimerization inhibitor. DEL-22379 taofia ERK Dimerization e aunoa ma le afaina o le ERK phosphorylation, puipuia le tumorigenesis e taʻitaʻia e RAS-ERK ala oncogenes. Toeitiiti atoa le 50% o faʻamaʻi pipisi o tagata faʻaalia le faʻamaoniaina o le RAS-ERK faʻamaonia; taofia o se fuafuaga aoga mo antineoplastic intervention.
Sini: ERK
