Divarasib,GDC 6036
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 0.1G | E tele | 550 |
| 0.5G | E tele | 860 |
| 1G | E tele | 1250 |
Igoa Vailaau:
1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl) prop-2-en-1-one
SMILES Code:
NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F
InChi Code:
InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32), 33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)
InChi Key:
ZRBPIAWWRPFDPY-UHFFFAOYSA-N
upu autu:
2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036
Solubility:SolubilityIa fuafuaina
Teuina:Mago, pogisa ma i le 0 - 4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi uumi (masina i tausaga).
Fa'amatalaga:
Divarasib (GDC-6036) o le KRAS G12C inhibitor faʻatasi ai ma le bioavailability oral ma le filifilia.
Sini: KRAS G12C inhibitor
