STING agonist-4

Izina ryimiti:

1,1 '- (butane-1,4-diyl) bis (2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1H-benzo [d] imidazole-5-carboxamide)

Kode ya SMILES:

O = C (C1 = CC = C2N (CCCCN3C (NC (C4 = CC (C) = NN4CC) = O) = NC5 = CC (C (N) = O) = CC = C35) C (NC (C6 = CC) (C) = NN6CC) = O) = NC2 = C1) N.

InChi Code:

InChI = 1S / C34H38N12O4 / c1-5-45-27 (15-19 (3) 41-45) 31 (49) 39-33-37-23-17-21 (29 (35) 47) 9-11- 25 (23) 43 (33) 13-7-8-14-44-26-12-10-22 (30 (36) 4 8) 18-24 (26) 38-34 (44) 40-32 (50) 28-16-20 (4) 42-46 (28) 6-2 / h9-12,15-18H, 5-8, 13-14H2,1-4H3, (H2,35,47) (H2,36,48) (H, 37,39,49) (H, 38,40,50)

InChi Urufunguzo:

ICZSAXDKFXTSGL-UHFFFAOYSA-N

Ijambo ryibanze:

Gukemura: 

Ububiko: 

Ibisobanuro:

STING agonist-4 ni moteri ya Interferon Genes (STING) reseptor agonist hamwe nikigaragara gihoraho (IC50) cya 20 nM. STING agonist-4 nuburyo bubiri bujyanye na amidobenzimidazole (ABZI) bushingiye ku guhuza ABZIs (diABZIs) hamwe no guhuza ibikorwa bya STING n'imikorere ya selile.

Intego: STING