CAT # | Izina ryibicuruzwa | Ibisobanuro |
CPD101235 | diABZI STING agonist-1 trihydrochloride | diABZI STING agonist-1 (trihydrochloride) ni ikintu gitera imbaraga za interferon genes (STING) reseptor agonist, hamwe na EC50s ya 130, 186 nM kubantu nimbeba. |
CPD101234 | diABZI STING agonist-1 (Tautomerism) | diABZI STING agonist-1 Tautomerism (compound 3) nikintu gitoranya gitera interferon genes (STING) reseptor agonist, hamwe na EC50s ya 130, 186 nM kubantu nimbeba. |
CPD101233 | diABZI STING agonist-1 | diABZI STING agonist-1 ni ikintu gitera imbaraga za interferon genes (STING) reseptor agonist, hamwe na EC50s ya 130, 186 nM kubantu nimbeba. |
CPD101232 | STING agonist-4 | STING agonist-4 ni moteri ya Interferon Genes (STING) reseptor agonist hamwe nikigaragara gihoraho (IC50) cya 20 nM. STING agonist-4 nuburyo bubiri bujyanye na amidobenzimidazole (ABZI) bushingiye ku guhuza ABZIs (diABZIs) hamwe no guhuza ibikorwa bya STING n'imikorere ya selile. |
CPD101231 | STING agonist-3 | STING agonist-3, yakuwe muri patenti WO2017175147A1 (urugero 10), ni ihitamo kandi itari nucleotide nto-molekile ntoya ya STING agonist hamwe na pEC50 na pIC50 ya 7.5 na 9.5. STING agonist-3 ifite ingaruka zirambye zo kurwanya ibibyimba kandi ifite imbaraga nyinshi zo kunoza imiti ya kanseri |