Trelagliptin

Dzina la Chemical:

(R) -2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

SMILES Kodi:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

InChi kodi:

InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14( 19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1

InChi Key:

IWYJYHUNXVAVAA-OAHLLOKOSA-N

Mawu ofunika:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Kusungunuka:Zosungunuka mu DMSO

Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

Kufotokozera:

Trelagliptin, yomwe imadziwikanso kuti SYR-472, ndi inhibitor ya dipeptidyl peptidase-4 (DPP-4) yomwe imapangidwa ndi Takeda pochiza matenda amtundu wa 2 (T2D). Chithandizo cha kamodzi pamlungu cha SYR-472 chimapanga kusintha kwakukulu pakuwongolera glycemic kwa odwala omwe ali ndi matenda amtundu wa 2. Zinaloledwa bwino ndipo zitha kukhala njira yatsopano yothandizira odwala omwe ali ndi matendawa. Trelagliptin (Zafatek(®)) idavomerezedwa ku Japan kuti azichiza matenda amtundu wa 2 mellitus (T2DM).

Cholinga: DPP-4