Sitagliptin
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
Paketi Kukula | Kupezeka | Mtengo (USD) |
Dzina la Chemical:
Sitagliptin (INN; yomwe idadziwika kale kuti MK-0431 ndipo idagulitsidwa pansi pa dzina lamalonda la Januvia) ndi mankhwala amkamwa a antihyperglycemic (anti-diabetes) a gulu la dipeptidyl peptidase-4 (DPP-4) inhibitor.
SMILES Kodi:
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O )(O)O.[H]O[H]
InChi kodi:
InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27- 13 (7- 26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1, 2,3,4);1H2/t9-;;/m1../s1
InChi Key:
GQPYTJVDPQTBQC-KLQYNRQASA-N
Mawu ofunika:
Sitagliptin, Sitagliptin phosphate, Januvia,Glactiv,ONO-5435, MK-0431, L-000224715, 654671-77-9,654671-78-0, 486460-32-6
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
Sitagliptin (INN; yomwe idadziwika kale kuti MK-0431 ndipo idagulitsidwa pansi pa dzina lamalonda la Januvia) ndi mankhwala amkamwa a antihyperglycemic (anti-diabetes) a gulu la dipeptidyl peptidase-4 (DPP-4) inhibitor. Anapangidwa ndipo amagulitsidwa ndi Merck & Co. Mankhwala oletsa ma enzymewa amagwiritsidwa ntchito okha kapena ophatikizana ndi oral antihyperglycemic agents (monga metformin kapena thiazolidinedione) pochiza matenda a shuga a mtundu wa 2. Ubwino wa mankhwalawa ndi zotsatira zake zotsika (mwachitsanzo, kuchepa kwa hypoglycemia, kuchepa thupi) pakuwongolera kuchuluka kwa shuga m'magazi. Exenatide (Byetta) imagwiranso ntchito ndi zotsatira zake pa incretin system.
Cholinga: DPP-4