Sitagliptin

Sitagliptin
  • Dzina:Sitagliptin
  • Catalog No.:Chithunzi cha CPDA0100
  • Nambala ya CAS:654671-77-9 (Sitagliptin Phosphate Monohydrate); 654671-78-0 (Sitagliptin Phosphate ); 486460-32-6 (m'munsi mwaulere)
  • Kulemera kwa Molecular:407.31
  • Chemical formula:Chithunzi cha C16H15F6N5O
  • Zofufuza zasayansi zokha, osati za odwala.

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    Zogulitsa Tags

    Paketi Kukula Kupezeka Mtengo (USD)

    Dzina la Chemical:

    Sitagliptin (INN; yomwe idadziwika kale kuti MK-0431 ndipo idagulitsidwa pansi pa dzina lamalonda la Januvia) ndi mankhwala amkamwa a antihyperglycemic (anti-diabetes) a gulu la dipeptidyl peptidase-4 (DPP-4) inhibitor.

    SMILES Kodi:

    O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O )(O)O.[H]O[H]

    InChi kodi:

    InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27- 13 (7- 26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1, 2,3,4);1H2/t9-;;/m1../s1

    InChi Key:

    GQPYTJVDPQTBQC-KLQYNRQASA-N

    Mawu ofunika:

    Sitagliptin, Sitagliptin phosphate, Januvia,Glactiv,ONO-5435, MK-0431, L-000224715, 654671-77-9,654671-78-0, 486460-32-6

    Kusungunuka:Zosungunuka mu DMSO

    Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

    Kufotokozera:

    Sitagliptin (INN; yomwe idadziwika kale kuti MK-0431 ndipo idagulitsidwa pansi pa dzina lamalonda la Januvia) ndi mankhwala amkamwa a antihyperglycemic (anti-diabetes) a gulu la dipeptidyl peptidase-4 (DPP-4) inhibitor. Anapangidwa ndipo amagulitsidwa ndi Merck & Co. Mankhwala oletsa ma enzymewa amagwiritsidwa ntchito okha kapena ophatikizana ndi oral antihyperglycemic agents (monga metformin kapena thiazolidinedione) pochiza matenda a shuga a mtundu wa 2. Ubwino wa mankhwalawa ndi zotsatira zake zotsika (mwachitsanzo, kuchepa kwa hypoglycemia, kuchepa thupi) pakuwongolera kuchuluka kwa shuga m'magazi. Exenatide (Byetta) imagwiranso ntchito ndi zotsatira zake pa incretin system.

    Cholinga: DPP-4


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