Mtengo wa SB-204990

Dzina la Chemical:

trans-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid

SMILES Kodi:

O=C(O)C[C@@]1(O)C(O[C@H](CCCCCCC2=CC=C(Cl)C=C2Cl)C1)=O

InChi kodi:

InChI=1S/C18H22Cl2O5/c19-13-8-7-12(15(20)9-13)5-3-1-2-4-6-14-10-18(24,11-16(21) 22)17(23)25-14/h7-9,14,24H,1-6,10-11H2,(H,21,22)/t14-,18-/m1/s1

InChi Key:

YTRNLFYTHYWDAU-RDTXWAMCSA-N

Mawu ofunika:

SB-204990, SB 204990, SB204990

Kusungunuka: 

Posungira: 

Kufotokozera:

SB-204990 ndi mankhwala amphamvu ATP citrate-lyase inhibitor SB-201076. SB-204990, pamene idaperekedwa pakamwa kwa makoswe, idalowetsedwa mu kayendedwe ka kayendedwe kake, pharmacologically yokhudzana ndi SB-201076 inapezedwa m'chiwindi. SB-204990 (25 mg/kg patsiku) idachepetsanso kuchuluka kwa cholesterol m'magazi (mpaka 23%) ndi triglyceride (mpaka 38%) mwa galu, makamaka kuchepetsa otsika osalimba lipoprotein poyerekeza ndi high-density lipoprotein cholesterol. milingo. SB-204990 ndi puloteni yofunikira pakuwongolera gawo lapansi la lipid synthesis de novo komanso chandamale cha enzyme chothandizira kulowererapo kwa hypolipidemic.

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