ATP citrate-lyase

MPAKA #	Dzina lazogulitsa	Kufotokozera
Chithunzi cha CPD3611	Mtengo wa SB-204990	SB-204990 ndi mankhwala amphamvu ATP citrate-lyase inhibitor SB-201076. SB-204990, pamene idaperekedwa pakamwa kwa makoswe, idalowetsedwa mu kayendedwe ka kayendedwe kake, pharmacologically yokhudzana ndi SB-201076 inapezedwa m'chiwindi. SB-204990 (25 mg/kg patsiku) idachepetsanso kuchuluka kwa cholesterol m'magazi (mpaka 23%) ndi triglyceride (mpaka 38%) mwa galu, makamaka kuchepetsa otsika osalimba lipoprotein poyerekeza ndi high-density lipoprotein cholesterol. milingo. SB-204990 ndi puloteni yofunikira pakuwongolera gawo lapansi la lipid synthesis de novo komanso chandamale cha enzyme chothandizira kulowererapo kwa hypolipidemic.