OTS964
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
Paketi Kukula | Kupezeka | Mtengo (USD) |
1g | Zilipo | 1750 |
Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
(R) -9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-imodzi
SMILES Kodi:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3)=C(O)C=C2C)C4=C1SC =C4
InChi kodi:
InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1
InChi Key:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Mawu ofunika:
OTS 964, OTS-964, OTS964, 1338545-07-5
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)
Kufotokozera:
OTS964 ndi inhibitor ya lymphokine-activated killer T cell-origined protein kinase (TOPK; IC50 = 28 nM). Imaletsa makamaka cytokinesis, zomwe zimatsogolera ku apoptosis, m'maselo ambiri a khansa. OTS964 imapangitsa apoptosis ya khansa ya m'mapapo ya anthu mu mbewa xenografts.
Cholinga: TOPK