Ertugliflozin

Dzina la Chemical:

(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3 , 4-zitatu

SMILES Kodi:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(O3)(CO4)CO)O)O)O)Cl"

InChi kodi:

"InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) )18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18 -,19-,20+,21-,22-/m0/s1 "

InChi Key:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

Mawu ofunika:

Ertugliflozin, PF 04971729,MK-8835,1210344-57-2

Kusungunuka:Zosungunuka mu DMSO

Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

Kufotokozera:

Ertugliflozin, yemwe amadziwikanso kuti PF-04971729, ndi choletsa champhamvu komanso chosankha cha sodium-dependent glucose cotransporter 2 komanso wodwala matenda amtundu wa 2 mellitus. Kafukufuku wazachipatala adawonetsa kuti Ertugliflozin (1-25 mg / tsiku) imawongolera kuwongolera kwa glycemic, kulemera kwa thupi komanso kuthamanga kwa magazi mwa odwala omwe ali ndi T2DM omwe amawongoleredwa pang'ono ndi metformin, ndipo amalekerera bwino.

Zolinga: SGLT-2