Ziftomenib；KO539

Ingoa:(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Nama Putumōhio:CPD113642

Nama CAS:2134675-36-6

Taumaha rāpoi:717.87

Tātai matū:C33 H42 F3 N9 O2 S2

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Taipitopito Hua

Tohu Hua

Rahi o te kete	Te waatea	Utu (USD)
0.1G	Kei roto i nga taonga	650
0.5G	Kei roto i nga taonga	970
1G	Kei roto i nga taonga	1350

Ingoa matū:

(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Waehere SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Waehere InChi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47) 19-45-25(18-37)15-27-22(2)23(5-6-29(27)45)20-42-9-7-24(8-10-42) )39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6, 15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1

Kī InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Kupumatua:

2134675-36-6；CAS：2134675-36-6；CAS:2134675-36-6；Ziftomenib; KO539; KO 539; KO-539

Wairewa:Hei whakatau

Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko te Ziftomenib (KO-539) he aukati i te taunekeneke menin MLL me te mahi waha.

Whainga: menin-MLL

Tōmua: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

Panuku: N-Methyl-5-(piperazin-1-yl)picolinamide hydrochloride