SJ-01

Ingoa matū:

(E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one

Waehere SMILES:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

Waehere InChi:

InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

Kī InChi:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Kupumatua:

20069-09-4；CAS:20069-09-4；CAS:20069-09-4；Piperlongumine; Piplatine.

Wairewa:Wairewa i roto i te DMSO

Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko te Piperlongumine, e mohiotia ana ko Piplartine, he pāhare koiora/amide mai i nga pepa, mai i te pepa roa (Piper longum L. - Piperaceae). Ko te pepa roa tetahi o nga mea tino whakamahia ki te rongoa Ayurvedic, e whakamahia ana hei rongoa i nga mate maha, tae atu ki nga pukupuku. Ko nga mahi rongoa o te piplartine ko te cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, and . I roto i nga hua rongoa maha o te piplartine, ko tana taonga anticancer te mea tino pai.

Whainga: Ko te Piperlongumine he pāhare e aukati ana i te hurihanga o nga myofibroblasts ma te aukati i te ara tohu erk1/2