PRT 543; C220; te aukati PRMT5

Ingoa matū:

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chlorophenyl)-hydroxymethyl]oxolane-3,4 -diol

Waehere SMILES:

O[C@H]1[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H]([C@@H](C4=CC=C(Cl)C =C4)O)[C@H]1O

Waehere InChi:

InChI=1S/C17H17ClN4O4/c18-9-3-1-8(2-4-9)11(23)14-12(24)13(25)17(26-14)22-6-5-10- 15(19)20-7-21-16(10)22/h1-7,11-14,17,23-25H,(H2,19,20,21)/t11-,12+,13-,14 -,17-/m1/s1

Kī InChi:

ITEKIFMGFZAFPM-QFRSUPTLSA-N

Kupumatua:

1989620-03-2；CAS:1989620-03-2；CAS:1989620-03-2；PRT-543; PRT543; PRT 543; C220; te aukati PRMT5; PRMT5 aukati C220

Wairewa: 

Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko te PRMT5-IN-35 (Compound 87) he aukati PRMT5 whai hua me te mahi a-waha.

Whāinga: PRMT5