NST-628

Ingoa matū:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

Waehere SMILES:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

Waehere InChi:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26 ,28)

Kī InChi:

YQSZJOABXRROQR-UHFFFAOYSA-N

Kupumatua:

3002056-30-3；CAS:3002056-30-3；CAS:3002056-30-3；NST-628；NST628；NST 628

Wairewa: 

Rokiroki:He maroke, he pouri me te 0 -4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko te NST-628 he MAPK molecular gel me te uruhanga arai toto-roro, ka taea te aukati i te phosphorylation RAF me te whakahohe MEK.

Whainga: RAF phosphorylation me MEK