Momelotinib; CTY387
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Ingoa matū:
N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pirimidin-4-yl)benzamide
Waehere SMILES:
O=C(NCC#N)C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1
Waehere InChi:
InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19- 5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27, 28)
Kī InChi:
ZVHNDZWQTBEVRY-UHFFFAOYSA-N
Kupumatua:
1056634-68-4,CAS:1056634-68-4;CAS:1056634-68-4;Momelotinib;CTY387;CYT-387;CYT 387
Wairewa:Wairewa i roto i te DMSO, DMF
Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).
Whakaahuatanga:
Ko te Momelotinib (CYT387) he whakataetae JAK1/JAK2 aukati o ATP.
Whainga: JAK1/JAK2