Waikawa Chenodeoxycholic

Ingoa matū:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl )waikawa pentanoic

Waehere SMILES:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Waehere InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Kī InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Kupumatua:

474-25-9，CAS:474-25-9，CAS：474-25-9，Chenodeoxycholic Acid， Anthropodeoxycholic acid，Anthropodesoxycholic acid，CCRIS 2195，Chendol，chenic acid; Chenix, waikawa Chenodeoxycholic, waikawa Chenodesoxycholic, Chenodiol, waikawa Gallodesoxycholic, NSC 657949, Xenbilox

Wairewa:Wairewa ki DMSO, kaua ki te wai

Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (nga ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau)

Whakaahuatanga:

Ko te Chenodiol, e mohiotia ana ko Chenodeoxycholic Acid me te waikawa chenocholic, he waikawa papa. Ka puta mai he matū tioata ma e kore e rewa ki te wai engari ka whakarewahia ki te waipiro me te waikawa ahetiki, me te ira whakarewa i te 165-167 °C. Ko nga tote o tenei waikawa carboxylic e kiia ana ko te chenodeoxycholates. Kua whakamahia te waikawa Chenodeoxycholic hei rongoa rongoa ki te whakakore i nga kowhatu. Ka taea te whakamahi i te waikawa Chenodeoxycholic ki te maimoatanga o te xanthomatosis cerebrotendineous. The Australian biotechnology company Giaconda has tested a treatment for Hepatitis C infection that combines chenodeoxycholic acid with bezafibrate.

Whainga: Whakahohe te kaiwhina karihi FXR