SB-204990

Nomen chemicum:

trans-5-[6-(2,4-Dichlorophenyl)hexyl] tetrahydro-3-hydroxy-2-oxo-3-furanaceticum

SMILES Code:

O=C(O)C[C@@]1(O)C(O[C@H](CCCCCC2=CC=C(Cl)C=C2Cl)C1)=O

InChi Code:

InChI=1S/C18H22Cl2O5/c19-13-8-7-12(15(20)9-13)5-3-1-2-4-6-14-10-18(24,11-16(21). 22) 17(23)25-14/h7-9,14,24H,1-6,10-11H2,(H,21,22)/t14-,18-/m1/s1

InChi Key:

YTRNLFYTHYWDAU-RDTXWAMCSA-N

Keyword:

SB-204990, SB 204990, SB204990

Solubilitas: 

Repono: 

Descriptio:

SB-204990 est productor potentis ATP inhibitoris citrati-lyasi SB-201076. SB-204990, cum viva voce ad mures administraretur, in circulationem systemicam absortus est, pharmacologice concentrationes SB 201076 in hepate receptas. SB-204990 (25 mg/kg per diem) plasma cholesteroli decrevit etiam gradus (ab usque ad 23%) et triglyceride gradus (ab usque ad 38%) in cane, potius decrescentes humilem densitatem lipoprotein cum summo densitate lipoprotein cholesteroli. gradus. SB-204990 momenti enzyme est in substrata moderandi copia synthesis lipidi de novo et potentiale enzyme scopo pro interventu hypolipidaemica.

Scopum: