Resmetirom

Resmetirom
  • Nomen:Resmetirom
  • Catalogue No.CPD1841
  • CAS No.:920509-32-6
  • Pondus hypotheticum:435.22
  • Formulae chemica:C17H12Cl2N6O4
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    Resmetirom

    SMILES Code:

    N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O

    InChi Code:

    InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25- 17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3;

    InChi Key:

    FDBYIYFVSAHJLY-UHFFFAOYSA-N

    Keyword:

    MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom

    Solubilitas:Solutum in DMSO, non in aqua

    Repono:0 - 4 C ad terminum brevem (dies ad septimanas), vel -20 C ad terminum longum (menses)

    Descriptio:

    Resmetirom, etiam ut MGL-3196, potens est et valde selectiva thyroideae hormone receptor β agonist in iudiciis clinicis ad tractationem dyslipidemiae. Effectus commodi thyreoidis hormonum in lipidorum graduum imprimis ob actionem in hormone receptore β (THR-β) in hepate, dum adversa effectus, inclusus effectus cardiaci, mediantur per hormone receptoris thyroideae α (THR. -α).

    Target: THR-β


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