| CAT # | Product Name | Descriptio |
| CPD100608 | ASK1-Inhibitor-10 | ASK1 Inhibitor 10 inhibitor oretenus inhibitor apoptosis kinasi signo-regularis 1 (ASK1). Est selectiva pro ASK1 super ASK2 ac MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, B-RAF. Streptozotocino inductum auget in JNK et p38 phosphorylationem in INS-1 pancreaticis β cellulis modo concentratione-dependens. |
| CPD100607 | K811 | K811 est inhibitor specialium ASK1 qui prolongat superstes in exemplari musculi amyotrophici lateralis sclerosis. K811 efficaciter impediuntur cellulae multiplicatio in lineis cellulis altis expressionibus ASK1 et in her2 cellulis GC superexpressis. Curatio cum K811 magnitudinum tumorum xenografti imminutarum per notas proliferation downregulando. |
| CPD100606 | K812 | K812 inhibitor specialium ASK1 repertus est ut diu superstes in exemplari musculi amyotrophici lateralis sclerosis. |
| CPD100605 | MSC-2032964A | MSC 2032964A inhibitor est potens et selectivus ASK1 (IC50 = 93 nM). LPS inductum ASK1 et p38 phosphorylationem in mus astrocytis excultis impedit et neuroinflammationem in muris EAE exemplar reprimit. MSC 2032964A ore efficax est et cerebrum penetrans. |
| CPD100604 | Selonsertib | Selonsertib, quae etiam GS-4997 notum est, oretenus bioavailable inhibitor kinasi 1 (ASK1), cum potentialibus anti-inflammatoriis, antineoplasticis et anti-fibroticis actionibus inhibitor est. GS-4997 scuta et ad catalyticum kinasem dominium ASK1 obligat in modo ATP-competitive, impediens eius phosphorylationem et activationem. GS-4997 vetat productionem cytokinorum inflammatoriis, deorsum regulat expressionem generum fibrosi implicatam, apoptosin nimiam reprimit et multiplicationem cellulosam prohibet. |
