Luxdegalutamide; ARV-766

Nomen chemicum:

4-(4-(1-(4-(((1r,3r)-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4- yl) methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamide

SMILES Code:

CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F)F)C(C(N[C@@H]6C(=O)NC(=O) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1

InChi Code:

InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)58-5)50- 39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23-21-51) 32-11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28; 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,49,54,57)/t36-,42-,43-/m0 /s1

InChi Key:

RDPPBRKNBBXPNZ-FMPIRMQTSA-N

Keyword:

2750830-09-0；CAS：2750830-09-0；CAS:2750830-09-0；ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide

Solubilitas: 

Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

Descriptio:

Luxdegalutamide (ARV-766) est viva hydrolysis dapibus chimaerica iaculis (PROTAC) receptaculum nisl androgenium (AR), quod resistentiam mutatam cognatam degradare potest AR.

Target: AR