Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Nomen chemicum:

(2R)-N-(3-{5-fluoro-2-[2-fluoro-3-(methanesulfonyl)anilino]pyrimidin-4-yl}-1H-indol-7-yl)-methoxy-2- (4-methylpiperazin-1-yl) propanamide

SMILES Code:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)[C@H](N5CCN(C )CC5)COC

InChi Code:

InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/ h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

InChi Key:

JNUZADQZHYFJGW-JOCHJYFZSA-N

Keyword:

2241039-81-4；CAS：2241039-81-4；CAS:2241039-81-4； Londonocitinib；JAK1-IN-7；AZD4604；AZD-4604；JAC34RRR7S

Solubilitas: 

Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

Descriptio:

Londamocitinib (AZD4604) est inhibitor efficax selectivum JAK1.

Target: JAK1