GSK2330672; linerixibat

Nomen chemicum:

Acidum pentanedioicum 3-((((3R,5R) -3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4- benzothiazepin-8-yl) methyl)amino)-

SMILES Code:

O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2( =O)=O)CC(O)=O

InChi Code:

InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15- 26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27; 29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1

InChi Key:

CZGVOBIGEBDYTP-VSGBNLITSA-N

Keyword:

1345982-69-5； CAS：1345982-69-5；CAS: 1345982-69-5；GSK-2330672; GSK 2330672; GSK2330672; linerixibat

Solubilitas:Solutum in DMSO

Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

Descriptio:

Linerixibat (GSK2330672) valde efficax, non absorbabilis, et viva voce top sodium dependens bile acidum transportatorem (ASBT) inhibitorem.

Target: ASBT