BMS-955176
Product Detail
Product Tags
Pack Size | Availability | Pretium (USD) |
Nomen chemicum:
4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino) -5a,5b,8,8,11a -pentamethyl-1 -(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro -1H-cyclopenta[a]chrysen-9-yl)benzoic acidum
SMILES Code:
O=C(O)C1=CC=C(C2=CC[C@@]3(C)[C@@](C2(C)C)([H])CC[C@@]4(C )[C@]5(C)CC[C@](C C[C@H]6C(C)=C)(NCCN(CC7)CCS7(=O)=O)[C@@]6([H])[C@@]5([H])CC[ C@]34[H])C=C1
InChi Code:
InChI=1S/C42H62N2O4S/c1-28(2)31-14-19-42(43-22-23-44-24-26-49(47,48)27-25-44)21-20-40( 6) 33(36(31)42)12-13-35-39(5)17-15-32(29-8-10-30(11-9); -29)37(45)46)38(3,4)34(39)16-18-41(35,40)7/h8-11,15,31,33-36,43H,1,12-14 ,16-27H2,2-7H3,(H,45,46)/t31-,33+,34-,35+,36+,39-,40+,41+,42-/m0/s1
InChi Key:
XDMUFNNPLXHNKA-ZTESCHFWSA-N
Keyword:
GSK3532795, GSK-3532795, GSK 3532795, BMS-955176, BMS 955176, BMS955176
Solubilitas:
Repono:
Descriptio:
GSK3532795, etiam ut notum est BMS-955176, est potens, viva voce activa, secundae generationis HIV-1 maturationis inhibitoris (MI) quae per periodum IIb iudiciis clinicis provectus est. GSK3532795 lata componit coverage virus polymorphicum (EC50<15 nM versus decuriam polymorphismi communis repraesentati 96.5% HIV-1 subtypi B viri) cum favorabili profile pharmacokineticae in speciebus preclinicis.
Target: HIV-1 maturation inhibitor (MI)