diABZI ACULUM agonist-1

Nomen chemicum:

(E) -1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol -1-yl) sed-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7-methoxy-1H-benzo[d]imidazole-5- carboxamide

SMILES Code:

O=C(N)C1=CC(N=C(NC(C2=CC(C))=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C))NN5CC)=O) = NC6=C4C(OCCN7CCOCC7)=CC(C(N)=O)=C6)=C3C(OC)=C1

InChi Code:

InChI=1S/C42H51N13O7/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43)56)23-33( 60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20-26(4) 50-55(32)7-2)22-28(38(44)57)24-34(36)62-16-10-11-51-14-17-61-18-15-51/h8- 9,19-24H,6-7,10-18H2,1-5H3(H2,43,56)(H2,44,57) /b9-8+

InChi Key:

JGLMVXWAHNTPRF-CMDGGOBGSA-N

Keyword:

Solubilitas: 

Repono: 

Descriptio:

diABZI STIO agonist-1 est stimulator genesis interfe- ricatorum (STING) receptor agonist, with EC50s of 130, 186 nM for human and mure, respectively.

Scopum: STING