BMS-986165

BMS-986165
  • Nomen:BMS-986165
  • Catalogue No.CPD100099
  • CAS No.:1609392-279
  • Pondus hypotheticum:425.45
  • Formulae chemica:C20 H22 N8 O3
  • Investigationes scientificae tantum, non aegros.

    Product Detail

    Product Tags

    Pack Size Availability Pretium (USD)
    10mg In Stock 260
    100mg In Stock 530
    1g In Stock 1350

    Nomen chemicum:

    6-(cyclopropanecarboxamido) -4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3) pyridazini-3 -carboxamide

    SMILES Code:

    O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[ 2H]

    InChi Code:

    InChI=1S/C20H22N8O3/c1-21-20(30)16-14(9-15(25-26-16)24-19(29)11-7-8-11)23-13-6-4- 5-12(17(13)31-3)18-22-10-28(2)27-18/h4-6,9-11H,7-8H2,1-3H3(H,21,30)( H2,23,24,25,29)/i1D3

    InChi Key:

    BZZKEPGENYLQSC-FIBGUPNXSA-N

    Keyword:

    1609392-279;CAS:1609392-7-9;CAS:1609392-27-9;BMS-986165; BMS 986165; BMS986165; Deucravacitinib

    Solubilitas:Solutum in DMSO

    Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

    Descriptio:

    BMS-986165 potentissima et selectiva Allosteric Inhibitor of TYK2. BMS-986165 Clausus Il-12, IL-23 et typus I Interferon Signaling et providet ad Robust Efficaciam in Preclinical Exemplar Inflammatorii Viscus Morbus. MS-986165 potenter obligat ad dominium pseudokinasi Tyk2 (Ki = 0.02 nM), et valde selectivam contra tabulam 265 kinases et pseudokinases. Compositum potenter inhibuit IL-23-, IL-12-, et Typus I cellularum interferon-actarum significativas et responsiones transcriptiones (IC50 range 2-14 nM).

    Target: TYK2


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