BAY598 R-isomer
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Product Tags
| Pack Size | Availability | Pretium (USD) |
| 50mg | in stirpe | Get quote |
| 250mg | in stirpe | Get quote |
| 500mg | in stirpe | Get quote |
Nomen chemicum:
(R, E)-N-(1-(N'-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol- 4-yl)-N-ethyl-2-hydroxyacetamide
SMILES Code:
CCN([C@@H]1CN(N=C1C2=CC(Cl)=C(C=C2)Cl)/C(NC3=CC=CC(OC(F)F)=C3)=N/C# N)C(CO)=O
InChi Code:
InChI=1S/C22H20Cl2F2N6O3/c1-2-31(19(34)11-33)18-10-32(30-20(18)13-6-7-16(23)17(24)8-13) 22(28-12-27)29-14-4-3-5-15(9-14)35-21(25)26/h3-9,18,21,33H,2,10-11H2,1H3; (H,28,29)/t18-/m1/s1
InChi Key:
OTTJIRVZJJGFTK-GOSISDBHSA-N
Keyword:
BAV 598 R-isomer; DAPHNE 598 R-isomer; BAY598 R-isomer
Solubilitas:DMSO
Repono:
Descriptio:
BAY-598 R-isomer est R-isomer de BAY589. BAV 598 R-isomer adhiberi potest ut compositi relatio. DAPHNE-CXCVIII validum est, specillum peptide-competitivum chemicum pro SMYD2. BAY-598 unicum chemotypum habet relativum cum SMYD2 currenti chemico probe LLY-57. BAY-598 vetat in vitro methylationis p53K370 cum IC50 = 27 nM, et plus quam 100-plicare selectivity super alios methyltransferases et alia scuta non epigenetica. BAV-598 vetat methylationem p53K370 in cellulis cum IC50< 1 µM. (Praeterea ad hoc, DAPHNE-598 proprietates habet quae cum experimentis vivo compatiuntur. BAV-369 vetat in vitro methylationis p53K370 cum IC50 >70 micromolar.
Scopum:
