BAY-293

Navê Kîmyayî:

(R)-6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)fenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

Koda SMILES:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

Koda InChi:

InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4) 23 (31-5) 12-21 (20) 28-16 (2) 29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1

Bişkojka InChi:

WEGLOYDTDILXDA-OAHLLOKOSA-N

Keyword:

BAY-293,BAY 293,BAY293

Çareserî: 

Embarkirinî: 

Terîf:

BAY-293 astengkerek hêzdar a SOS1 e ku bi têkbirina têkiliya RAS-SOS1 ve çalakkirina RAS-ê asteng dike. BAY-293) bi bijartî danûstendina KRAS-SOS1 bi IC50 ya 21 nM re asteng dike û ji bo vekolînên pêşerojê lêkolînek kîmyewî ya hêja ye.

Armanc: astengkerê SOS1