TNG462

Jeneng Kimia:

N-(6-amino-5-etilpiridin-3-yl)-2-(5-metil-2-(2-(1-metilpiperidin-4-yl)benzo[d]tiazol-5-yl)piperidin-1 -yl) -2-oxoacetamide

Kode SMILES:

O=C(NC1=CC(CC)=C(N)N=C1)C(N1[C@@H](C2=CC=C3C(N=C(S3)C3CCN(C)CC3)=C2) CC[C@H](C)C1)=O

Kode Inchi:

InChI=1S/C28H36N6O2S/c1-4-18-13-21(15-30-25(18)29)31-26(35)28(36)34-16-17(2)5-7-23( 34)20-6-8-24-22(14-20)32-27(37-24)19-9-11-33(3)12-10-19/h6,8,13-15,17, 19,23H,4-5,7,9-12,16H2,1-3H3,(H2,29,30)(H,31,35)/t17-,23+/m0/s1

Kunci InChi:

DHAGMIPSRSPWSH-GAJHUEQPSA-N

tembung kunci:

2760483-96-1；CAS:2760483-96-1；CAS:2760483-96-1；TNG462；TNG 462；TNG-462

Kelarutan: 

Panyimpenan:Garing, peteng lan ing 0 -4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

TNG-462 minangka inhibitor PRMT5 selektif sing efektif sacara lisan.

Sasaran: PRMT5