KUCING # | Jeneng produk | Katrangan |
CPD101235 | diABZI STING agonis-1 trihidroklorida | diABZI STING agonist-1 (trihydrochloride) minangka stimulator selektif saka gen interferon (STING) reseptor agonis, kanthi EC50s 130, 186 nM kanggo manungsa lan tikus, masing-masing. |
CPD101234 | diABZI STING agonist-1 (Tautomerism) | diABZI STING agonist-1 Tautomerism (senyawa 3) minangka stimulator selektif saka gen interferon (STING) reseptor agonis, kanthi EC50s saka 130, 186 nM kanggo manungsa lan mouse, mungguh. |
CPD101233 | diaABZI STING agonis-1 | diABZI STING agonist-1 minangka stimulator selektif saka agonis reseptor gen interferon (STING), kanthi EC50s 130, 186 nM kanggo manungsa lan tikus. |
CPD101232 | STING agonis-4 | Agonis STING-4 minangka stimulator saka agonis reseptor Interferon Genes (STING) kanthi konstanta inhibisi sing jelas (IC50) 20 nM. STING agonis-4 minangka senyawa adhedhasar amidobenzimidazole (ABZI) sing gegandhengan karo simetri kanggo nggawe ABZIs (diABZIs) sing disambungake kanthi ikatan sing luwih apik kanggo STING lan fungsi seluler. |
CPD101231 | STING agonis-3 | STING agonist-3, diekstrak saka paten WO2017175147A1 (conto 10), minangka agonis STING molekul cilik sing selektif lan non-nukleotida kanthi pEC50 lan pIC50 saka 7,5 lan 9,5. STING agonist-3 nduweni efek anti-tumor sing tahan lama lan potensial banget kanggo ningkatake perawatan kanker |