OTS964

OTS964
  • jeneng:OTS964
  • No. Katalog:CPDB0996
  • Nomer CAS:1338545-07-5
  • Bobot molekul:392.5
  • Formula kimia:C23H24N2O2S
  • Kanggo riset ilmiah mung, ora kanggo pasien.

    Detail Produk

    Tag produk

    Ukuran Paket kasedhiyan Rega (USD)
    1g Ing Simpenan 1750
    Ukuran liyane Entuk Kutipan Entuk Kutipan

    Jeneng Kimia:

    (R)-9-(4-(1-(dimethylamino)propan-2-yl)fenil)-8-hydroxy-6-methylthieno[2,3-c]kuinolin-4(5H)-siji

    Kode SMILES:

    [H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3)=C(O)C=C2C)C4=C1SC =C4

    Kode Inchi:

    InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1

    Kunci InChi:

    YHPWOYBWUWSJDW-UQKRIMTDSA-N

    tembung kunci:

    OTS 964, OTS-964, OTS964, 1338545-07-5

    Kelarutan:Larut ing DMSO

    Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi)

    katrangan:

    OTS964 minangka inhibitor protein kinase asal sel T sing diaktifake lymphokine (TOPK; IC50 = 28 nM). Iki khusus ngalangi sitokinesis, sing nyebabake apoptosis, ing macem-macem sel kanker. OTS964 nyebabake apoptosis sel kanker paru-paru manungsa ing xenografts mouse.

    Sasaran: TOPK


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