OTS964
Detail Produk
Tag produk
Ukuran Paket | kasedhiyan | Rega (USD) |
1g | Ing Simpenan | 1750 |
Ukuran liyane | Entuk Kutipan | Entuk Kutipan |
Jeneng Kimia:
(R)-9-(4-(1-(dimethylamino)propan-2-yl)fenil)-8-hydroxy-6-methylthieno[2,3-c]kuinolin-4(5H)-siji
Kode SMILES:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3)=C(O)C=C2C)C4=C1SC =C4
Kode Inchi:
InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1
Kunci InChi:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
tembung kunci:
OTS 964, OTS-964, OTS964, 1338545-07-5
Kelarutan:Larut ing DMSO
Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi)
katrangan:
OTS964 minangka inhibitor protein kinase asal sel T sing diaktifake lymphokine (TOPK; IC50 = 28 nM). Iki khusus ngalangi sitokinesis, sing nyebabake apoptosis, ing macem-macem sel kanker. OTS964 nyebabake apoptosis sel kanker paru-paru manungsa ing xenografts mouse.
Sasaran: TOPK