GDC-0077

Jeneng Kimia:

(S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oksazepin-9-yl)amino)propanamida

Kode SMILES:

C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1

Kode Inchi:

InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11) 24)2 5-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26 )/t9-,12-/m0/s1

Kunci InChi:

SGEUNORSOZVTOL-CABZTGGNLSA-N

tembung kunci:

GDC-0077; GDC 0077; GDC0077

Kelarutan:DMSO

Panyimpenan: 

katrangan:

GDC-0077 minangka inhibitor PI3K sing kasedhiya kanthi lisan kanthi aktivitas antineoplastik potensial. GDC-0077 diekstrak saka paten WO 2017001645 A1, rumus I.

Sasaran: PI3K