EAI-045

EAI-045
  • jeneng:EAI-045
  • No. Katalog:CPDB0934
  • Nomer CAS:1942114-09-1
  • Bobot molekul:383.4
  • Formula kimia:C19H14FN3O3S
  • Kanggo riset ilmiah mung, ora kanggo pasien.

    Detail Produk

    Tag produk

    Ukuran Paket kasedhiyan Rega (USD)

    Jeneng Kimia:

    2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide

    Kode SMILES:

    O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O

    Kode Inchi:

    InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)

    Kunci InChi:

    YTUFHOKUFOQRDF-UHFFFAOYSA-N

    tembung kunci:

    EAI-045, EAI045, EAI 045, 1942114-09-1

    Kelarutan:Larut ing DMSO

    Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi)

    katrangan:

    EAI045 minangka inhbitor EGFR sing kuat lan selektif. EAI045 target mutan EGFR tahan obat sing dipilih nanging nyisakke reseptor jinis liar. EAI045 nyegah L858R / T790M-mutant EGFR kanthi potensial nano-nanomolar ing tes biokimia.

    Sasaran: EGFR


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