EAI-045
Detail Produk
Tag produk
Ukuran Paket | kasedhiyan | Rega (USD) |
Jeneng Kimia:
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
Kode SMILES:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
Kode Inchi:
InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
Kunci InChi:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
tembung kunci:
EAI-045, EAI045, EAI 045, 1942114-09-1
Kelarutan:Larut ing DMSO
Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi)
katrangan:
EAI045 minangka inhbitor EGFR sing kuat lan selektif. EAI045 target mutan EGFR tahan obat sing dipilih nanging nyisakke reseptor jinis liar. EAI045 nyegah L858R / T790M-mutant EGFR kanthi potensial nano-nanomolar ing tes biokimia.
Sasaran: EGFR