Verucerfont

Aha kemịkalụ:

(S) -3- (4-methoxy-2-methylphenyl) -2,5-dimethyl-N- (1- (3-methyl-1,2,4-oxadiazol-5-yl) propyl) pyrazolo [1, 5-a]pyrimidin-7-amine

Koodu Ọchịchọ:

CC[C@H](NC1=CC(C)=NC2=C(C3=CC=C(OC)C=C3C)C(C)=NN12)C4=NC(C)=NO4

Koodu InChi:

InChi=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28 19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1

Igodo InChi:

VKHVAUKFLBBZFJ-SFHVURJKSA-N

Okwu:

Verucerfont, GSK561679, GSK 561679, GSK-561679, NBI77860, NBI 77860, NBI-77860, 885220-61-1

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

"Verucerfont, nke a makwaara dị ka GSK561679 na NBI77860, bụ onye na-emegide CRF-1. Verucerfont na-egbochi onye na-anabata CRH-1, ya mere na-ebelata ntọhapụ ACTH na-esote nrụgide na-adịghị ala ala. A na-enyocha ya dị ka ọgwụgwọ nwere ike ịṅụ mmanya na-aba n'anya, n'ihi na nrụgide na-adịghị ala ala na-abụkarị mgbe. Ihe na-akpata ma mmepe nke aṅụrụma na nlọghachi azụ n'ịgbake ndị aṅụrụma, egosila nsonaazụ na-ekwe nkwa na ọmụmụ anụmanụ mana a nwalebeghị ya n'ime mmadụ.

Ebumnuche: CRF-1