BAY-1895344

Aha kemịkalụ:

(R) -3-methyl-4- (4- (1-methyl-1H-pyrazol-5-yl) -8- (1H-pyrazol-5-yl) -1,7-naphthyridin-2-yl) morpholine

Koodu Ọchịchọ:

CN1N=CC=C1C2=CC(N3[C@H](C)COCC3=NC4=C(C5=CC=NN5)N=CC=C24.[H]Cl

Koodu InChi:

InChI=1S/C20H21N7O.ClH/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6- 21-2 0 (19 (14) 24-18) 16-4-7-22-25-16;/h3-8,11,13H,9-10,12H2,1-2H3, (H,22,25);1H /t13-;/m1./s1

Igodo InChi:

KWQNBYGUBHMRPY-BTQNPOSSSA-N

Okwu:

1876467-74-1;CAS:1876467-74-1;CAS:1876467-74-1;BAY-1895344,BAY1895344,BAY 1895344

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

BAY-1895344 bụ onye na-egbochi ATR (ataxia-telangiectasia na protein protein Rad3) nke na-egbochi mgbasawanye nke ahịrị mkpụrụ ndụ tumor mmadụ (median IC50 = 78 nM). Emepụtara BAY-1895344 maka ọgwụgwọ ndị ọrịa nwere etuto siri ike na lymphomas dị elu, ọ na-agakwa usoro nnwale ụlọ ọgwụ nke mbụ nke nchekwa na nnabata maka ndị ọrịa kansa.

Ebumnuche: ATR