Vactosertib
Nkọwa ngwaahịa
Mkpado ngwaahịa
Nha ngwugwu | Nnweta | Ọnụ ego (USD) |
500mg | Dị na ngwaahịa | 800 |
1g | Dị na ngwaahịa | 1300 |
5g | Dị na ngwaahịa | 3800 |
Nha ndị ọzọ | Nweta Quotes | Nweta Quotes |
Aha kemịkalụ:
N- ((4- ([1,2,4]triazolo [1,5-a] pyridin-6-yl) -5- (6-methylpyridin-2-yl) -1H-imidazol-2-yl) methyl -2-fluoroaniline
Koodu Ọchịchọ:
FC1=CC=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
Koodu InChi:
InChi=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28- 19 (29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
Igodo InChi:
FJCDSQATIJKQKA-UHFFFAOYSA-N
Okwu:
Vactosertib, EW-7197, EW7197, EW 7197, 1352608-82-2
Solubility:Soluble na DMSO
Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)
Nkọwa:
Vactosertib, nke a makwaara dị ka EW-7197 bụ ihe mgbochi ALK5 nwere ike. EW-7197 gosipụtara ike na vivo mgbochi metastatic, na-egosi ike ya maka iji ya dị ka ọgwụgwọ ọrịa cancer. EW-7197 na-egbochi akara ngosi TGF-β/Smad. EW-7197 na-ewepụ TGF-β1 na-ebute mbugharị cell tumor na mbuso agha. EW-7197 na-egbochi metastasis nke ọrịa ara ara na ngụgụ.EW-7197 na-agbatị ndụ ụmụ oke BALB/c 4T1 site na mgbochi nke EMT. EW-7197 na-egbochi metastasis ma kwalite ọrụ cytotoxic T lymphocytes (CTLs) na ụmụ oke 4T1 orthotopic anyadokwa.
Ebumnuche: ALK