Vactosertib

Vactosertib
  • Aha:Vactosertib
  • Nọmba katalọgụ:CPD3325
  • Nọmba CAS:1352608-82-2
  • Arọ Molecular:399.42
  • Usoro kemịkalụ:C22H18FN7
  • Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Nha ngwugwu Nnweta Ọnụ ego (USD)
    500mg Dị na ngwaahịa 800
    1g Dị na ngwaahịa 1300
    5g Dị na ngwaahịa 3800
    Nha ndị ọzọ Nweta Quotes Nweta Quotes

    Aha kemịkalụ:

    N- ((4- ([1,2,4]triazolo [1,5-a] pyridin-6-yl) -5- (6-methylpyridin-2-yl) -1H-imidazol-2-yl) methyl -2-fluoroaniline

    Koodu Ọchịchọ:

    FC1=CC=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2

    Koodu InChi:

    InChi=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28- 19 (29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)

    Igodo InChi:

    FJCDSQATIJKQKA-UHFFFAOYSA-N

    Okwu:

    Vactosertib, EW-7197, EW7197, EW 7197, 1352608-82-2

    Solubility:Soluble na DMSO

    Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)

    Nkọwa:

    Vactosertib, nke a makwaara dị ka EW-7197 bụ ihe mgbochi ALK5 nwere ike. EW-7197 gosipụtara ike na vivo mgbochi metastatic, na-egosi ike ya maka iji ya dị ka ọgwụgwọ ọrịa cancer. EW-7197 na-egbochi akara ngosi TGF-β/Smad. EW-7197 na-ewepụ TGF-β1 na-ebute mbugharị cell tumor na mbuso agha. EW-7197 na-egbochi metastasis nke ọrịa ara ara na ngụgụ.EW-7197 na-agbatị ndụ ụmụ oke BALB/c 4T1 site na mgbochi nke EMT. EW-7197 na-egbochi metastasis ma kwalite ọrụ cytotoxic T lymphocytes (CTLs) na ụmụ oke 4T1 orthotopic anyadokwa.

    Ebumnuche: ALK


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