TAS-120

Aha kemịkalụ:

1-[(3S) -3-[4-amino-3-[2- (3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo [3,4-d] pyrimidin-1-yl] -1-pyrrolidinyl -2-propen-1-otu

Koodu Ọchịchọ:

C=CC(N1C[C@@H](N2N=C(C#CC3=CC(OC)=CC(OC)=C3)C4=C(N)N=CN=C42)CC1)=O

Koodu InChi:

InChi=1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28) 6-5-14-9-16 (30-2) 11-17 (10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2 ,23,24,25)/t15-/m0/s1

Igodo InChi:

KEIPNCCJPRMIAX-HNNXBMFYSA-N

Okwu:

TAS-120

Solubility: 

Nchekwa: 

Nkọwa:

TAS-120 bụ onye na-egbochi ọnụ nke bioavailable inhibitor nke fibroblast growth factor receptor (FGFR) nwere ọrụ antineoplastic nwere ike. FGFR inhibitor TAS-120 na-ahọrọ ma na-agbanweghi agbanwe na-ejikọta ma na-egbochi FGFR, nke nwere ike ịkpata nkwụsị nke ma ụzọ ntụgharị mgbaàmà nke FGFR na mmụba cell tumor, na ụbara ọnwụ cell na FGFR-na-egosipụta oke mkpụrụ ndụ tumor. FGFR bụ tyrosine kinase nnabata nke dị mkpa maka mmụba cell tumor, ọdịiche na nlanarị na okwu ya na-edozi n'ọtụtụ ụdị cell tumor.

Ebumnuche: FGFR