ND-630
Nkọwa ngwaahịa
Mkpado ngwaahịa
| Nha ngwugwu | Nnweta | Ọnụ ego (USD) |
| 10mg | Dị na ngwaahịa | 300 |
| 50mg | Dị na ngwaahịa | 500 |
| 100mg | Dị na ngwaahịa | 800 |
| Nha ndị ọzọ | Nweta Quotes | Nweta Quotes |
Aha kemịkalụ:
(R) -2- (1- (2- (2-methoxyphenyl)) -2- ((tetrahydro-2H-pyran-4-yl) oxy) ethyl) -5-methyl-6- (oxazol-2-yl) -2,4-dioxo-1,2-dihydrothieno[2,3-d] pyrimidin-3 (4H) -yl)-2-methylpropanamide
Koodu Ọchịchọ:
O=C(N)C(C)(C)N(C(N(C[C@@H])(C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC= CO5)S3)=O)C4=O
Koodu InChi:
InChi=1S/C28H31N3O8S/c1-16-21-24(32)31(28(2,3)26(33)34)27(35)30(25(21)40-22(16)23-29- 11-14-38-23)15-20 (39-17-9-12-37-13-10-17)18-7-5-6-8-19(18)36-4/h5-8, 11,14,17,20H,9-10,12-13,15H2,1-4H3,(H,33,34)/t20-/m0/s1
Igodo InChi:
ZZWWXIBKLBMSCS-FQEVSTJZSA-N
Okwu:
ND-630, ND630, ND 630, GS-0976, GS0976, GS 0976, NDI-010976, NDI010976, NDI 010976, Firsocostat, 1434635-54-7
Solubility:Soluble na DMSO
Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).
Nkọwa:
ND-630 na-egbochi hACC1 (IC50=2.1±0.2 nM) na hACC2 (IC50=6.1±0.8 nM). Mgbochi bụ mgbanwe na nke ukwuu kpọmkwem maka ACC. ND-630 na-egbochi ọrụ ACC site na imekọrịta ihe n'ime phosphopeptide-anabata na dimerization saịtị nke enzyme iji gbochie dimerization. ND-630 na-egbochi njikọ fatty acid na EC50 nke 66 nM n'ime sel HepG2 na-agbanweghị ọnụ ọgụgụ cell mkpokọta, ntinye protein cellular, na ntinye nke acetate n'ime cholesterol[1].
Ebumnuche: ACC
