GSK2256098
Nkọwa ngwaahịa
Mkpado ngwaahịa
Nha ngwugwu | Nnweta | Ọnụ ego (USD) |
100mg | Dị na ngwaahịa | 450 |
1g | Dị na ngwaahịa | 2000 |
Nha ndị ọzọ | Nweta Quotes | Nweta Quotes |
Aha kemịkalụ:
2-((5-chloro-2- ((1-isopropyl-3-methyl-1H-pyrazol-5-yl) amino) pyridin-4-yl) amino) -N-methoxybenzamide
Koodu Ọchịchọ:
CC1=NN(C(=C1)NC2=NC=C(C(=C2)NC3=CC=CC=C3C(=O)NOC)Cl)C(C)C
Koodu InChi:
InChi=1S/C20H23ClN6O2/c1-12(2)27-19(9-13(3)25-27)24-18-10-17(15(21)11-22-18)23-16-8- 6-5-7-14 (16)20(28)26-29-4/h5-12H,1-4H3,(H,26,28)(H2,22,23,24)
Igodo InChi:
BVAHPPKGOOJSPU-UHFFFAOYSA-N
Okwu:
GSK2256098, GSK-2256098, GSK 2256098, GTPL7939, GTPL 7939, GTPL-7939, 1224887-10-8
Solubility:Soluble na DMSO
Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).
Nkọwa:
GSK2256098, makwaara dị ka GTPL7939, bụ adhesion kinase-1 (FAK) inhibitor nwere ike antiangiogenic na antineoplastic omume. FAK inhibitor GSK2256098 na-egbochi FAK, nke nwere ike igbochi ntinye aka nke integrin nke ọtụtụ ụzọ ntụgharị mgbaàmà mgbada, gụnyere ERK, JNK/MAPK na PI3K/Akt, si otú ahụ na-egbochi mbugharị cell tumor, proliferation and survival, and tumor angiogenesis. A na-arụ ọrụ FAK tyrosine kinase site na ijikọ na integrins na matrix extracellular (ECM) mana enwere ike meziwanye ya yana mekwaa ya n'ụdị cell tumor dị iche iche.
Ebumnuche: FAK