GSK2256098

GSK2256098
  • Aha:GSK2256098
  • Nọmba katalọgụ:CPDB1021
  • Nọmba CAS:1224887-10-8
  • Arọ Molecular:414.894
  • Usoro kemịkalụ:C20H23ClN6O2
  • Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Nha ngwugwu Nnweta Ọnụ ego (USD)
    100mg Dị na ngwaahịa 450
    1g Dị na ngwaahịa 2000
    Nha ndị ọzọ Nweta Quotes Nweta Quotes

    Aha kemịkalụ:

    2-((5-chloro-2- ((1-isopropyl-3-methyl-1H-pyrazol-5-yl) amino) pyridin-4-yl) amino) -N-methoxybenzamide

    Koodu Ọchịchọ:

    CC1=NN(C(=C1)NC2=NC=C(C(=C2)NC3=CC=CC=C3C(=O)NOC)Cl)C(C)C

    Koodu InChi:

    InChi=1S/C20H23ClN6O2/c1-12(2)27-19(9-13(3)25-27)24-18-10-17(15(21)11-22-18)23-16-8- 6-5-7-14 (16)20(28)26-29-4/h5-12H,1-4H3,(H,26,28)(H2,22,23,24)

    Igodo InChi:

    BVAHPPKGOOJSPU-UHFFFAOYSA-N

    Okwu:

    GSK2256098, GSK-2256098, GSK 2256098, GTPL7939, GTPL 7939, GTPL-7939, 1224887-10-8

    Solubility:Soluble na DMSO

    Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

    Nkọwa:

    GSK2256098, makwaara dị ka GTPL7939, bụ adhesion kinase-1 (FAK) inhibitor nwere ike antiangiogenic na antineoplastic omume. FAK inhibitor GSK2256098 na-egbochi FAK, nke nwere ike igbochi ntinye aka nke integrin nke ọtụtụ ụzọ ntụgharị mgbaàmà mgbada, gụnyere ERK, JNK/MAPK na PI3K/Akt, si otú ahụ na-egbochi mbugharị cell tumor, proliferation and survival, and tumor angiogenesis. A na-arụ ọrụ FAK tyrosine kinase site na ijikọ na integrins na matrix extracellular (ECM) mana enwere ike meziwanye ya yana mekwaa ya n'ụdị cell tumor dị iche iche.

    Ebumnuche: FAK


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